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INHERITANCE OF SUSCEPTIBILITY TO FRIEND MOUSE LEUKEMIA VIRUS

✍ Scribed by Takeshi Odaka

Book ID
115174181
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
156 KB
Volume
18
Category
Article
ISSN
1320-5463

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## Abstract Based on the previous observation that a single major autosomal locus controls susceptibility to Friend leukemia virus in mice, an attempt was made to place the gene for resistance, Fv^r^, from resistant C57Bl/6 mice into the genetic background of susceptible D D D mice. The cross‐inter

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## Abstract Genetic control of splenomegaly which occurs at a late stage of Friend leukemia virus infection was studied in hybrid mice between DDD‐Fv^r^ and C57BL/6. It was demonstrated that this late splenomegaly was mainly controlled by a single autosomal locus with the dominant allele for resist

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## Abstract The genetic control of susceptibility to the Friend leukemia virus (FLV) complex was studied under conditions which excluded the effect of the Fv locus. From hybrids between two mouse lines which have the same Fv genotype, but differ from each other in response to FLV infection, partial

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Inheritance of susceptibility to friend mouse leukemia virus. X. Separate genetic control of two viruses in friend virus preparation
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## Abstract Susceptibility of mice to viral components present in Friend leukemia virus (FLV) preparation, lymphatic leukemia virus (LLV) and spleen focus‐forming virus (SFFV), was studied by separately determining end point for infection of each component. Mice with __Fv‐1^n^__ genotype were much

Inheritance of susceptibility to friend
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✍ Takeshi Odaka; Haruo Sugano; Kiyoshi Takizawa πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 French βš– 825 KB

## Abstract The effect of the __Fv__ locus on the pathogenesis of Friend virus‐induced leukemia was studied with two pairs of mouse strains which are congenic except for the locus. The rapid spleen enlargement or spleen focus formation which is characteristic of Friend virus infection occurred in t