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Infrared study of helix strandedness in the poly A-poly U system

✍ Scribed by H.Todd Miles; Joe Frazier

Book ID: 118848268
Publisher: Elsevier Science
Year: 1963
Tongue: English
Weight: 311 KB
Volume: 14
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(63)90204-3

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## Synopsis Studies were made of the influence of hydrostatic pressure on the helix-coil transitions of poly(A + U) and poly(A + 2U). The results were analyzed by a thermodynamic treatment which emphasized the cooperative aspect of the transitions. The helix-to-coil volume changes were found to be

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## Abstract The slow kinetics of annealing processes in multistranded nucleic acids is spectrophotometrically investigated using poly(A)·2poly(U) as a model system. The absorbance changes at specific wavelengths show that double‐helical (A·U) base pairs appear as transient intermediates. The anneal