Influence of food intake on electrocardiograms of healthy male volunteers
✍ Scribed by E. Widerlöv; K. -G. Jostell; L. Claesson; B. Odlind; M. Keisu; U. Freyschuss
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 205 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0031-6970
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The effect of food on the pharmacokinetics of the antiepileptic rufinamide was investigated in healthy volunteers. Twelve subjects were treated with single pre-oral doses of 600 mg of rufinamide after overnight fasting or a fat and protein rich breakfast. Mean (+/- S.D.) areas under the plasma conce
ty of brolxomine hyr!rocfiioride was investigated t healthy male volunteers were g i x n Tingle peroral r 'hy'rochloride after overnight fasting or a fpt-a:d proteiniich breakfast Mean ( : b SL)) areas under the plasma concentration-time curves (AUC) were 9 -5 6 (2\*j5)prm11 h when g i e n to he fas