Induction of urokinase-type plasminogen activator and its receptor in the gastric fibroblasts and effects of nonsteroidal anti-inflammatory drugs and prostaglandin
โ Scribed by Jun-Ichi Iwamoto; Yuji Mizokami; Kimiko Takahashi; Takeshi Matsuoka
- Book ID
- 119427713
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 175 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0016-5085
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## Background: The authors found previously that plasma levels of urokinase-type plasminogen activator (upa) and its receptor (upar) were elevated in patients with bladder carcinoma and were associated with features of biologically aggressive disease. in the current study, they tested the hypothesi
The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in tumour invasion. Previous studies have shown by RT-PCR that uPA and uPAR mRNAs are expressed in human hepatocellular carcinoma (HCC). Here, in situ hybridization, immunohistochemistry, and double immunoยฏ