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Urinary level of urokinase-type plasminogen activator and its receptor in the detection of bladder cancer

โœ Scribed by R. Casella; S. Shariat; M. Monoski; S. Lemer

Book ID
118644594
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
185 KB
Volume
2
Category
Article
ISSN
1569-9056

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## Background: The authors found previously that plasma levels of urokinase-type plasminogen activator (upa) and its receptor (upar) were elevated in patients with bladder carcinoma and were associated with features of biologically aggressive disease. in the current study, they tested the hypothesi

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## Urokinase -type plasminogen activator (u-PA) is thought to be implicated in cancer invasion and metastasis. The aim of this study was to determine whether the u-PA content of cancer tissue is a prognostic factor in bladder cancer. Tissue samples from 46 patients with bladder cancer were assesse