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Induction of sister chromatid exchanges by hydroxylamine, hydrazine and isoniazid and their inhibition by cysteine

✍ Scribed by G. Speit; C. Wick; M. Wolf

Publisher
Springer
Year
1980
Tongue
English
Weight
320 KB
Volume
54
Category
Article
ISSN
0340-6717

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Induction of sister chromatid exchanges
Induction of sister chromatid exchanges by pyrimethamine in human lymphocyte cultures
✍ Ünal Egeli πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 51 KB πŸ‘ 2 views

This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m