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Induction of sister chromatid exchanges and bacterial revertants by organic extracts of airborne particles

✍ Scribed by Lockard, J. M. ;Viau, C. J. ;Lee-Stephens, C. ;Caldwell, J. C. ;Wojciechowski, J. P. ;Enoch, H. G. ;Sabharwal, P. S.

Publisher
Wiley (John Wiley & Sons)
Year
1981
Weight
683 KB
Volume
3
Category
Article
ISSN
0192-2521

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Induction of sister chromatid exchanges
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This study examined the effect of pyrimethamine (PYR) on sister chromatid exchanges (SCEs) in human lymphocytes. PYR is a folic acid antagonist used for the treatment of malaria and toxoplasmosis. PYR was added to peripheral blood lymphocyte cultures at three different doses: 0.05, 0.1, and 0.2 mg/m