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Induction of organ-selective CD4+ regulatory T cell homing

✍ Scribed by Christiane Siewert; Astrid Menning; Jan Dudda; Kerstin Siegmund; Uta Lauer; Stefan Floess; Daniel J. Campbell; Alf Hamann; Jochen Huehn


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
489 KB
Volume
37
Category
Article
ISSN
0014-2980

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## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR