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Regulatory circuits in autoimmunity: recruitment of counter-regulatory CD8+ T cells by encephalitogenic CD4+ T line cells

✍ Scribed by Deming Sun; Avraham Ben-Nun; Hartmut Wekerle

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
666 KB
Volume
18
Category
Article
ISSN
0014-2980

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## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos