Human CD4+FOXP3+ regulatory T cells produce CXCL8 and recruit neutrophils
β Scribed by Megan E. Himmel; Sarah Q. Crome; Sabine Ivison; Ciriaco Piccirillo; Theodore S. Steiner; Megan K. Levings
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 299 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Current literature suggests that T cells recognizing antigen on mature dendritic cells (DC) differentiate into effector T cells whereas tolerance is induced when antigen is presented by immature DC. We investigated the consequences of the interactions between immature or lipopolysacchar
The transcription factor FOXP3 plays a key role in CD4 + CD25 + regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4 + CD25 + cells that express FOXP3 protein