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Single-cell dynamics of mast cell–CD4+CD25+ regulatory T cell interactions

✍ Scribed by Barbara Frossi; Federica D'Incà; Enrico Crivellato; Riccardo Sibilano; Giorgia Gri; Marco Mongillo; Luca Danelli; Laura Maggi; Carlo E. Pucillo

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
560 KB
Volume
41
Category
Article
ISSN
0014-2980

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## Abstract Although the phenotypic and regulatory properties of the CD4^+^CD25^+^ T cell lineage (Treg cells) have been well described, the specificities remain largely unknown. We demonstrate here that the CD4^+^CD25^+^ Treg population includes the recognition of a broad spectrum of human TCR CDR