Induction of oncornavirus-like particles in cell line of canine mammary carcinoma
✍ Scribed by Watrach, A M; Hager, J C; Wong, P K; Watrach, M A; MacLeod, R
- Book ID
- 109833813
- Publisher
- Nature Publishing Group
- Year
- 1978
- Tongue
- English
- Weight
- 738 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0007-0920
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## Abstract An oncornavirus‐like agent has been described in HeLa cells of human origin (Gelderblom __et al.__, 1974). The investigation of its protein constituents revealed a pattern similar to but different from that of known oncornaviruses. Six polypeptides with molecular weights (mw) between 12
## Abstract Oncornavirus‐like particles observed and purified from HeLa cell culture supernates have a density in sucrose of 1.16‐1.17 g/cm^3^. They contain DNA polymerase and ribonuclease activities with properties characteristic of reverse transcriptase and ribonuclease H of known oncornaviruses.