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Induction of Notch signaling by tumor necrosis factor in rheumatoid synovial fibroblasts

✍ Scribed by Ando, Kiichiro; Kanazawa, Satoshi; Tetsuka, Toshifumi; Ohta, Shusuke; Jiang, Xu; Tada, Toyohiro; Kobayashi, Masaaki; Matsui, Nobuo; Okamoto, Takashi


Book ID
110068051
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
489 KB
Volume
22
Category
Article
ISSN
0950-9232

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Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor a (TNFa). Seven of 12 sera from RA patients contained TNFa, while only 1 of those from reactive arthritis patients was positive.