𝔖 Bobbio Scriptorium
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INDUCTION OF DNA-STRAND BREAKS IN CULTURED HUMAN FIBROBLASTS BY REACTIVE METABOLITES

✍ Scribed by Magnus Nordenskjöld; Peter Moldéus


Book ID
118721099
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
131 KB
Volume
407
Category
Article
ISSN
0890-6564

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In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure