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Induction and repair of DNA double-strand breaks in human fibroblasts after particle irradiation

✍ Scribed by M Löbrich


Book ID
108427235
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
768 KB
Volume
22
Category
Article
ISSN
0273-1177

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In vitro exposure of normal human diploid fibroblasts (strain VH-10) to ethylene oxide (EtO) induced DNA strand breaks in the dose range of 2.5-30 mMh of EtO. Alkaline DNA unwinding (ADU), neutral filter elution (NFE), pulsed field gel electrophoresis (PFGE), and the comet assay were used to measure