𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Induction, modification and inhibition of rat liver microsomal benzo(a)pyrene hydroxylase; Correlation with the S-9-mediated mutagenicity of benzo(a)pyrene

✍ Scribed by C. Razzouk; E. Agazzi-Léonard; J. Cumps; F. Poncelet; M. Mercier; M. Roberfroid


Book ID
118312419
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
566 KB
Volume
85
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


The metabolic activation of benzo(a)pyre
✍ Ronald A. Lubet; Jorge Capdevila; Russell A. Prouoh 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 French ⚖ 473 KB 👁 1 views

## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex

Rat liver microsome-mediated binding of
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 422 KB 👁 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy