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Suppressed mutagenicity of benzo[a]pyrene by the liver S9 fraction and microsomes from eugenol-treated rats

✍ Scribed by Hiroshi Yokota; Jiro Hoshino; Akira Yuasa


Book ID
119092918
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
456 KB
Volume
172
Category
Article
ISSN
0165-1218

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex