The metabolic activation of benzo(a)pyre
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Ronald A. Lubet; Jorge Capdevila; Russell A. Prouoh
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Article
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1979
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John Wiley and Sons
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French
β 473 KB
π 1 views
## Abstract A rat liver microsomeβmediated bacterial mutagenicity test showed 9βhydroxybenzo (__a__) pyrene to be significantly more effective as a preβmutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex