Indole Derivatives as a New Class of Steroid 5α-Reductase Inhibitors
✍ Scribed by Takami, Hitoshi; Koshimura, Hirokazu; Kishibayashi, Nobuyuki; Ishii, Akio; Nonaka, Hiromi; Aoyama, Shiro; Kase, Hiroshi; Kumazawa, Toshiaki
- Book ID
- 126962538
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 179 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-2623
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## Abstract The spiro[cyclohexane‐1,2′‐[2__H__]indene] derivatives 15a,b with molecular dimensions and nucleophilic functional groups similar to known steroid 5α‐reductase inhibitors (__e.g.__ 2) were synthesized. The spiro[cyclohexane‐1,2′‐[2__H__]indene]‐1′(3′__H__),4‐dione (5) was synthesized fr