New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
✍ Scribed by Yazmín Arellano; Eugene Bratoeff; Mariana Garrido; Juan Soriano; Yvonne Heuze; Marisa Cabeza
- Book ID
- 116892650
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 387 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0039-128X
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pyrrolebutyric Acid Derivatives as Inhibitors of Steroid 5α-Reductase. -A series of pyrrolebutyric acid derivatives (I) (37 examples) are synthesized and evaluated for their inhibitory activity on steroid 5α-reductase in vitro and ex vivo. The calcium salt of (Id) shows potent inhibitory activities