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Increased sensitivity to adriamycin and reversal of resistance to cisplatin by cyclosporin a or emetine in ovarian carcinoma cell lines

โœ Scribed by D.G. Mutch; T.J. Herzog; C-A. Chen; J. Rader; M-S. Kao; J.L. Collins


Book ID
119054251
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
166 KB
Volume
45
Category
Article
ISSN
0090-8258

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Two sublines were derived from a human bladder carcinoma continuous cell line (RTI 12-P), one by exposure to fractionated X-irradiation (RTI IZ-DXRa) and the other by continuous exposure to cisplatin (RT 112-CP). RTI I2-DXR8 cells were I .6to 2-fold more sensitive to cisplatin and 2 analogues, carbo