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Increased DT-diaphorase expression and cross-resistance to mitomycin C in a series of cisplatin-resistant human ovarian cancer cell lines

โœ Scribed by Peter J. O'Dwyer; Raymond P. Perez; Kang-Shen Yao; Andrew K. Godwin; Thomas C. Hamilton


Book ID
115784600
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
839 KB
Volume
52
Category
Article
ISSN
0006-2952

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This study was undertaken to elucidate the mechanism@) of cross-resistance to cisplatin (CDDP) in a mitomycin C (MMC)resistant human bladder cancer cell line, J82/MMC. The J82/ MMC cell line displayed 2-to 3-fold cross-resistance to CDDP and carboplatin when compared to the parental )82/WT cells. Dr