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A comparison of hyperthermia cisplatin sensitization in human ovarian carcinoma and glioma cell lines sensitive and resistant to cisplatin treatment

โœ Scribed by G. P. Raaphorst; S. Doja; L. Davis; D. Stewart; C. E. Ng


Publisher
Springer
Year
1996
Tongue
English
Weight
328 KB
Volume
37
Category
Article
ISSN
0344-5704

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Cellular sensitivity to cis-diamminedichloroplatinum(ll) (cDDP) can be regulated by protein kinase C (PKC) signal transduction pathway. Activators of PKC were shown to enhance the sensitivity of human ovarian carcinoma 2008 cells to cDDP. We have examined whether or not the PKC signal transduction p