𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Increased repair of O 6 -alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea

✍ Scribed by Bodell, William J.; Aida, Toshimitsui; Berger, Mitchell S.; Rosenblum, Mark L.


Book ID
121762454
Publisher
Oxford University Press
Year
1986
Tongue
English
Weight
539 KB
Volume
7
Category
Article
ISSN
0143-3334

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Contribution of O6-methylguanine-DNA met
✍ Michael S. Bobola; Mitchel S. Berger; John R. Silber πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 711 KB

## Abstract To assess the possible role of the DNA repair protein __O__^6^‐methylguanine‐DNA methyltransferase (MGMT) in resistance of brain neoplasms to the clinically important chloroethylating agent 1,3‐bis(2‐chloroethyl)‐1‐nitrosourea (BCNU), we quantitated MGMT activity, BCNU survival, and the