Inclusion Complexes of Felodipine and Amlodipine with Methyl-β-cyclodextrin
✍ Scribed by Jadwiga Mielcarek; Agnieszka Czernielewska; Beata Czarczyńska
- Publisher
- Springer Netherlands
- Year
- 2006
- Tongue
- English
- Weight
- 327 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0923-0750
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📜 SIMILAR VOLUMES
## Abstract An inclusion complex of fenbufen with β‐cyclodextrin (β‐CD) in aqueous solution was characterized by ^1^H‐NMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (__M__^−1^) was calculated. The geometry of the inclusion complex was established
AM1 semiempirical molecular orbital calculations have been performed Ž . on the inclusion complexes of -cyclodextrin -CD with methylated benzoic acids in two orientations, the ''head-first'' and ''tail-first'' positions. In the former, the CO H 2 group points toward the primary hydroxyls of the CD