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Inclusion complex of fenbufen with β-cyclodextrin

✍ Scribed by I. Bratu; J. M. Gavira-Vallejo; A. Hernanz; M. Bogdan; Gh. Bora


Publisher
Wiley (John Wiley & Sons)
Year
2004
Tongue
English
Weight
108 KB
Volume
73
Category
Article
ISSN
0006-3525

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✦ Synopsis


Abstract

An inclusion complex of fenbufen with β‐cyclodextrin (β‐CD) in aqueous solution was characterized by ^1^H‐NMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (M^−1^) was calculated. The geometry of the inclusion complex was established based on MM+ molecular mechanics calculations. © 2004 Wiley Periodicals, Inc. Biopolymers, 2004


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