Comparative study on inclusion complexations of antiinflammatory drug flurbiprofen with β-cyclodextrin and methylated β-cyclodextrins
✍ Scribed by Teruko Imai; Tetsumi Irie; Masaki Otagiri; Kaneto Uekama; Masaki Yamasaki
- Publisher
- Springer Netherlands
- Year
- 1984
- Tongue
- English
- Weight
- 412 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0923-0750
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AM1 semiempirical molecular orbital calculations have been performed Ž . on the inclusion complexes of -cyclodextrin -CD with methylated benzoic acids in two orientations, the ''head-first'' and ''tail-first'' positions. In the former, the CO H 2 group points toward the primary hydroxyls of the CD
The inclusion complexes of cyclomaltoheptaose (/3-CD) and /~-CD's 50% hydroxyethyl-substituted derivative (HE-/3-CD) with chlorogenic acid (CA) were studied with regard to temperature and water activity (all2 o = mole fraction = XH2 o = 0.8--0.99; 0.1 M Na phosphate buffer) utilizing first-derivativ
## Abstract [CpM(CO)__~n~__Cl] complexes with M = Fe (__n__ = 2) and Mo (__n__ = 3) have been immobilised in plain β‐cyclodextrin (β‐CD) and permethylated β‐CD (TRIMEB) by methods tailored according to the stabilities and solubilities of the individual components. Four adducts were obtained with a