✦ LIBER ✦

In vivo31P NMR spectroscopy of agonist-stimulated phosphatidylinositol metabolism in cat brain

✍ Scribed by Perry F. Renshaw; Mitchell D. Schnall; John S. Leigh Jr.

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 370 KB
Volume: 4
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910040303

No coin nor oath required. For personal study only.

✦ Synopsis

As a result of the agonist stimulation of muscarinic receptors, myo-inositol-1-phosphate accumulates in the presence of millimolar lithium concentrations. This accumulation of myo-inositol-1-phosphate can be detected by in vivo 31P NMR spectroscopy. Since myo-inositol-1-phosphate is a breakdown product of phosphatidylinositol, this may provide a means of noninvasively monitoring phosphatidylinositol metabolism in vivo.

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