𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In vivo MR microscopy of the human skin

✍ Scribed by Hee Kwon Song; Felix W. Wehrli; Jingfei Ma

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
853 KB
Volume
37
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The requirements for imaging the skin are dictated by the organ's layered structure, which extends only a few millimeters from the surface and thus demands extremely high resolution in this direction. While less critical, resolution in the remaining two dimensions determines whether the skin's accessory structures can be resolved. The problem is compounded by short transverse relaxation times, in particular of the dermis, the structure of most clinical interest. In this work images of the normal human skin were obtained in vivo at voxel sizes as small as 19 × 78 × 800 μm^3^, by means of customized 3D gradient and partial flip‐angle spin‐echo pulse sequences and very small transmit/receive coils on a 1.5T clinical imager equipped with high‐power whole‐body gradients. Structures resolved include hair follicles and the sublayers of the dermis. The very short time constant for the major component (91 %) for transverse relaxation in the dermis (T~2~* ∼10 ms) suggests the potential of substantial gains in achievable signal‐to‐noise ratio by shortening the echo time.

📜 SIMILAR VOLUMES

In vivo visualization of microneedle con
In vivo visualization of microneedle conduits in human skin using laser scanning microscopy
✍ S. Bal; A.C. Kruithof; H. Liebl; M. Tomerius; J. Bouwstra; J. Lademann; M. Meink 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB

Solid microneedles enhance the penetration of drugs into the viable skin but little is known about the geometry of the conduits in vivo. Therefore, laser scanning microscopy was used to visualize the conduits of a microneedle system with needles at a length of 300 μm in 6 healthy subjects over a per

In vivo imaging of Malassezia yeasts on
In vivo imaging of Malassezia yeasts on human skin using confocal laser scanning microscopy
✍ L. E. Meyer; N. Otberg; H.-J. Tietz; W. Sterry; J. Lademann 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

Fiber-based confocal laser scanning microscopy affords a vast field of application in medical research and clinical practice. The application of fluorescent dye allows real-time imaging of yeasts of the genus Malassezia on human skin __in vivo__. An Ar^+^-laser is used to excite the fluorescent food

In vivo phosphorus spectroscopy of human
In vivo phosphorus spectroscopy of human skin
✍ Daryl E. Bohning; Alexander C. Wright; Kenneth M. Spicer 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 811 KB

## Abstract Skin ^31^P MRS measurements might detect metabolic damage from irradiation, chemotherapy, or ischemia. Although rat and cadaver data have demonstrated this potential (C. D. Cuono, __et al.__, Wast __Reconstr. Surg__. 81,1–11 (1988), H. W. Klein, __et al., Ann. Plast Surg__. 20, 547–551

7 Tesla MR imaging of the human eye in v
7 Tesla MR imaging of the human eye in vivo
✍ Kathryn Richdale; Peter Wassenaar; Katharine Teal Bluestein; Amir Abduljalil; Jo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

## Abstract ## Purpose: To develop a protocol which optimizes contrast, resolution and scan time for three‐dimensional (3D) imaging of the human eye in vivo using a 7 Tesla (T) scanner and custom radio frequency (RF) coil. ## Materials and Methods: Initial testing was conducted to reduce motion

In vivo MRS measurement of deoxymyoglobi
In vivo MRS measurement of deoxymyoglobin in human forearms
✍ Zhiyue Wang; Elizabeth A. Noyszewski; John S. Leigh Jr. 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB 👁 1 views

## Abstract __In vivo__ MRS measurement of deoxymyoglobin (deoxy‐Mb) in human forearms was performed by observing the N‐δ proton of F8 proximal histidine. The concentration of deoxy‐Mb reflects the oxygen level in the muscle. In resting muscles, the deoxy‐Mb level was below the detection sensitivit

In vivo microscopy of a rat abdominal sk
In vivo microscopy of a rat abdominal skin flap: A new model
✍ Elizabeth B. Whan; John V. Hurley; Wayne A. Morrison 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB

## Abstract This study describes a rat abdominal skin flap model of in vivo microscopy which provides a reliable, easy to perform system in which to examine the microcirculation of flaps. The island flap, which is based on the superficial inferior epigastric vessels caudally, and drained proximally