Multiple drugs have been used in experimental skin flap models to reduce the effects of reperfusion ischemia. The effects of antiproteases, however, have not been studied. A skin flap ischemia reperfusion model was developed in the rat to study the effects that aprotinin, a broad-spectrum antiserine
In vivo microscopy of a rat abdominal skin flap: A new model
β Scribed by Elizabeth B. Whan; John V. Hurley; Wayne A. Morrison
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 254 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0738-1085
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
This study describes a rat abdominal skin flap model of in vivo microscopy which provides a reliable, easy to perform system in which to examine the microcirculation of flaps. The island flap, which is based on the superficial inferior epigastric vessels caudally, and drained proximally by the lateral thoracic vein, can be mounted directly on a Perspex microscope stage. In vivo microscopy of the subdermal plexus of the flap allows detailed study of blood flow pattern, capillary flow, microvessel diameter, and margination of leucocytes, in a skin flap with versatile blood supply and innervation. Β© 1994 WileyβLiss, Inc.
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