## BACKGROUND. The antimitotic agent paclitaxel is highly active in the therapy of several tumor types, including ovarian and breast cancer. The commercial formulation (TaxoP) is supplied in a vehicle containing alcohol and the surfactant Cremophor EL@ (polyethoxylated castor oil). Whereas Phase I
Skin ulceration potential of paclitaxel in a mouse skin model in vivo
β Scribed by Gianfilippo Bertelli; Mara A. Cafferata; Andrea Ardizzoni; Alberto Gozza; Riccardo Rosso; Dario Dini
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 266 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Integrins β£2β€1, β£3β€1, and β£6β€4 are expressed in the epidermis, and play an important role in wound healing and/or epidermal-dermal interaction. These integrins may provide a new perspective into the understanding of wound healing and vesication. The isolated perfused porcine skin flap (IPPSF) has be
## Abstract ## Objective Activated adhesive signaling is a hallmark of fibroblasts isolated from the scars of scleroderma (systemic sclerosis) lesions. Betaβ1 integrin plays a key role in adhesive signaling. The aim of the present study was to examine the role of Ξ²1 integrin in a mouse model of sk
Noninvasive techniques that provide detailed information about molecular composition, structure, and interactions are crucial to further our understanding of the relation between skin disease and biochemical changes in the skin, as well as for the development of penetration enhancers for transdermal
## Abstract ## Objective Tissue fibrosis is a hallmark compromising feature of many disorders. In this study, we investigated the antifibrogenic effects of the histone deacetylase inhibitor trichostatin A (TSA) on cytokineβdriven fibrotic responses in vitro and in vivo. ## Methods Skin fibroblas