In Vitro Toxicology Systems

✍ Scribed by Anna Bal-Price, Paul Jennings (eds.)

Publisher: Humana Press
Year: 2014
Tongue: English
Leaves: 585
Series: Methods in Pharmacology and Toxicology
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches.

Reliable and authoritative, In Vitro Toxicology Systems will be of benefit not only to students, scientists and regulators working in the field of chemical safety assessment but also to a wider scientific audience.

✦ Table of Contents

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Front Matter....Pages 3-23
Front Matter....Pages 25-25
Front Matter....Pages 27-44
Front Matter....Pages 45-77
Front Matter....Pages 79-101
Front Matter....Pages 103-121
Front Matter....Pages 123-123
Back Matter....Pages 125-146
....Pages 147-166

✦ Subjects

Pharmacology/Toxicology; Laboratory Medicine

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