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In vitro penetration of the dopamine D2 agonist N-0923 with and without Azone

✍ Scribed by P.J. Swart; W.L. Weide; R.A. De Zeeuw

Book ID
113365830
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
428 KB
Volume
87
Category
Article
ISSN
0378-5173

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## Abstract Certain aminotetralins are known to be potent dopamine D~2~ receptor agonists. N‐0923, [‐]2‐(N‐propyl‐N‐2‐thienylethylamino)‐5‐hydroxytetralin HCl, recognizes the high and low affinity states of the D~2~ receptor in membranes from bovine caudate with a K~low~ of 79 nM. The selectivity r