N-0923, a selective dopamine D2 receptor
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Dr. J. D. Belluzzi; E. F. Domino; J. M. May; K. S. Bankiewicz; D. A. McAfee
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Article
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2004
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John Wiley and Sons
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English
β 800 KB
## Abstract Certain aminotetralins are known to be potent dopamine D~2~ receptor agonists. Nβ0923, [β]2β(NβpropylβNβ2βthienylethylamino)β5βhydroxytetralin HCl, recognizes the high and low affinity states of the D~2~ receptor in membranes from bovine caudate with a K~low~ of 79 nM. The selectivity r