An zn vztro method has been developed for screening of candidate biomaterials in an early phase of their development. The test is based on L-929 mouse fibroblast cultures and their response to powdered polymer samples. I t applies microscopic observation for the detection of morphological changes, u
In Vitro and In Vivo Biocompatibility Testing of Absorbable Metal Stents
β Scribed by Loos, Anneke; Rohde, Roland; Haverich, Axel; Barlach, Sabine
- Book ID
- 121259419
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 207 KB
- Volume
- 253
- Category
- Article
- ISSN
- 1022-1360
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π SIMILAR VOLUMES
In the recent paper by R. M. Rice, et a1.l I am quoted as having said "that no compound which is nontoxic in uitro will be toxic by intramuscular implantation."2 The impression created is that this was a general conclusion reached by me in this review paper. In actuality, although a very similar sta
## Abstract An __in vivo__ method is described for screening polymeric materials for biocompatibility. The test is based on grading acute and subacute tissue reactions at 7 and 28 days, respectively, following implantation in rats. The method is reproducible and reliable. It is designed to provide