In search of the tumour-suppressor functions of BRCA1 and BRCA2
โ Scribed by Scully, Ralph; Livingston, David M.
- Book ID
- 109771629
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 188 KB
- Volume
- 408
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/35044000
No coin nor oath required. For personal study only.
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## Communicated by Richard Wooster Mutations in the BRCA1 and BRCA2 genes predispose women to breast and ovarian cancer. BRCA1 and BRCA2 are 83 and 86 kb long, with coding sequences of 5.7 and 10.2 kb, scattered over 22 and 26 coding exons, respectively. The large majority of the alterations ident