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Functional Domains of the BRCA1 and BRCA2 Proteins

โœ Scribed by Richard Baer; Wen-Hwa Lee


Book ID
110375683
Publisher
Springer US
Year
1998
Tongue
English
Weight
193 KB
Volume
3
Category
Article
ISSN
1083-3021

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## Abstract BRCA1 is a tumor suppressor gene that is mutated in families with breast and ovarian cancer. Several BRCA1 splice variants are found in different tissues, but their subcellular localization and functions are poorly understood at the moment. We previously described BRCA1 splice variant B