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Highlight: BRCA1 and BRCA2 proteins in breast cancer

✍ Scribed by Dianne C. Daniel


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
431 KB
Volume
59
Category
Article
ISSN
1059-910X

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## Abstract The __BRCA1__ gene was identified and cloned in 1994 based its linkage to early onset breast cancer and breast‐ovarian cancer syndromes in women. While inherited mutations of BRCA1 are responsible for about 40–45% of hereditary breast cancers, these mutations account for only 2‐3% of al