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Functional Characterization of BRCA1 and BRCA2: Clues from Their Interacting Proteins

✍ Scribed by Shyam K. Sharan; Allan Bradley

Book ID: 110376301
Publisher: Springer US
Year: 1998
Tongue: English
Weight: 223 KB
Volume: 3
Category: Article
ISSN: 1083-3021
DOI: 10.1023/a:1018788132560

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## Abstract BRCA1 is a tumor suppressor gene that is mutated in families with breast and ovarian cancer. Several BRCA1 splice variants are found in different tissues, but their subcellular localization and functions are poorly understood at the moment. We previously described BRCA1 splice variant B