✦ LIBER ✦

Impact of BRCA1 and BRCA2 variants on splicing: clues from an allelic imbalance study

✍ Scribed by Caux-Moncoutier, Virginie; Pagès-Berhouet, Sabine; Michaux, Dorothée; Asselain, Bernard; Castéra, Laurent; De Pauw, Antoine; Buecher, Bruno; Gauthier-Villars, Marion; Stoppa-Lyonnet, Dominique; Houdayer, Claude

Book ID: 109849186
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 181 KB
Volume: 17
Category: Article
ISSN: 1018-4813
DOI: 10.1038/ejhg.2009.89

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Splicing and multifactorial analysis of

Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary

✍ Phillip J. Whiley; Lucia Guidugli; Logan C. Walker; Sue Healey; Bryony A. Thomps 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB 👁 2 views

Clinical management of breast cancer families is complicated by identification of BRCA1 and BRCA2 sequence alterations of unknown significance. Molecular assays evaluating the effect of intronic variants on native splicing can help determine their clinical relevance. Twentysix intronic BRCA1/2 varia

Allelic loss of the BRCA1 and BRCA2 gene

Allelic loss of the BRCA1 and BRCA2 genes and other regions on 17q and 13q in breast cancer among women from Taiwan (area of low incidence but early onset)

✍ Yen-Li Lo; Jyh-Cherng Yu; Chiun-Sheng Huang; Su-Ling Tseng; Tzu-Ming Chang; King 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 456 KB 👁 1 views

We have examined the role of the breast cancer susceptibility genes BRCA1 and BRCA2 and other loci in the vicinity of these 2 genes on the long arms of chromosomes 17 and 13 (17q and 13q) for the presence of genomic deletions in breast cancer among Taiwanese women. Breast cancer in Taiwan is particu