Calcineurin inhibitors (CNIs) contribute to renal dysfunction following liver transplantation. This prospective, randomized, multicenter, 6-month study (with an additional 6 months of follow-up) evaluated whether everolimus with CNI reduction or discontinuation would improve renal function in mainte
✦ LIBER ✦
Improved Renal Function After Early Conversion From a Calcineurin Inhibitor to Everolimus: a Randomized Trial in Kidney Transplantation
✍ Scribed by L. Mjörnstedt; S. S. Sørensen; B. von zur Mühlen; B. Jespersen; J. M. Hansen; C. Bistrup; H. Andersson; B. Gustafsson; L.H. Undset; H. Fagertun; D. Solbu; H. Holdaas
- Book ID
- 114806514
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 640 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1600-6135
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Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro
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