Renal function in renal or liver transplant recipients after conversion from a calcineurin inhibitor to sirolimus
✍ Scribed by L. Bäckman; A. Varberg Reisæter; L. Wramner; B.-G. Ericzon; K. Salmela; C. Brattström
- Book ID
- 110889669
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 79 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0902-0063
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Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro
Renal impairment is common in patients after liver transplantation and is attributable in large part to the use of calcineurin inhibitor (CNI)-based immunosuppression. We sought to determine whether conversion to sirolimus-based immunosuppression was associated with improved renal function. In a sin