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Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus

✍ Scribed by Kyrsten D. Fairbanks; Joseph A. Eustace; Derek Fine; Paul J. Thuluvath


Book ID
111723439
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
87 KB
Volume
9
Category
Article
ISSN
1527-6465

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Renal impairment is common in patients after liver transplantation and is attributable in large part to the use of calcineurin inhibitor (CNI)-based immunosuppression. We sought to determine whether conversion to sirolimus-based immunosuppression was associated with improved renal function. In a sin

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The purpose of this study is to review the clinical experience with sirolimus immunosuppression in liver transplant patients with calcineurin inhibitor-induced chronic renal insufficiency. The study design is a case-control retrospective series. Fifty-seven liver transplant patients with renal insuf