Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus
β Scribed by Kyrsten D. Fairbanks; Joseph A. Eustace; Derek Fine; Paul J. Thuluvath
- Book ID
- 111723439
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 87 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1527-6465
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π SIMILAR VOLUMES
Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro
Renal impairment is common in patients after liver transplantation and is attributable in large part to the use of calcineurin inhibitor (CNI)-based immunosuppression. We sought to determine whether conversion to sirolimus-based immunosuppression was associated with improved renal function. In a sin
The purpose of this study is to review the clinical experience with sirolimus immunosuppression in liver transplant patients with calcineurin inhibitor-induced chronic renal insufficiency. The study design is a case-control retrospective series. Fifty-seven liver transplant patients with renal insuf