## Abstract There is concern that shear could cause protein unfolding or aggregation during commercial biopharmaceutical production. In this work we exposed two concentrated immunoglobulinβG1 (IgG1) monoclonal antibody (mAb, at >100 mg/mL) formulations to shear rates between 20,000 and 250,000 s^β1
Improved high-affinity monoclonal antibody to lododeoxyuridine
β Scribed by Martin Vanderlaan; Bruce Watkins; Cynthia Thomas; Frank Dolbeare; Larry Stanker
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 840 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0196-4763
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