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Improved acceptor polymers for enzymic glycosylation

✍ Scribed by Sabine Köpper; Uri Zehavi


Publisher
Elsevier Science
Year
1994
Weight
667 KB
Volume
22
Category
Article
ISSN
0923-1137

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✦ Synopsis


Different acceptor polymers for enzymic glycosylations were obtained by derivatising cross-linked polyacrylamide beads with various diamines and coupling of glucose via a light-sensitive glycosidic linkage. The carrier-bound glucose was shown to be an effective substrate in enzymic glycosylations with galactosyltransferase. A comparative study of the different acceptor polymers allowed for an evaluation of factors influencing the accessibility of the polymer-bound substrate.


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