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Improved, water-soluble, acceptor polymers for enzymic glycosylation

✍ Scribed by Alexandra Tuchinsky; Uri Zehavi

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
550 KB
Volume
31
Category
Article
ISSN
1381-5148

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✦ Synopsis

Two water-soluble polymers carrying 0.28 and 0.16 mmol glucose/g were prepared following the co-polymerization of 2-nitro-4-(carboxyhydrazido-N'-acryloyl)benzyl 2,3,4,6-tetra-O-acetyl-/I-n-glucopyranoside and arcylamide. The polymers served as efficient acceptors (up to 86% transfer yield) in the galactosyltransferase reaction and the product saccharide, lactose, was released from the polymers following photolysis (84% yield).

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