✦ LIBER ✦

Important Role of Translational Science in Rare Disease Innovation, Discovery, and Drug Development

✍ Scribed by Anne R. Pariser MD,William A. Gahl MD, PhD

Book ID: 126362453
Publisher: John Wiley and Sons
Year: 2014
Tongue: English
Weight: 122 KB
Volume: 29
Category: Article
ISSN: 0884-8734
DOI: 10.1007/s11606-014-2881-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Multifaceted roles of ultra-rare and rar

Multifaceted roles of ultra-rare and rare disease patients/parents in drug discovery

✍ Wood, Jill; Sames, Lori; Moore, Allison; Ekins, Sean 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 347 KB

The role of translational bioinformatics

The role of translational bioinformatics in drug discovery

✍ Natalie S. Buchan; Deepak K. Rajpal; Yue Webster; Carlos Alatorre; Ranga Chandra 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 278 KB

Lost in translation? Role of metabolomic

Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development

✍ Jan van der Greef; Aram Adourian; Pieter Muntendam; Robert N. McBurney 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 572 KB

Role of drug metabolism in drug discover

Role of drug metabolism in drug discovery and development

✍ Gondi N. Kumar; Sekhar Surapaneni 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 1 views

## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t

Enzyme Inhibition in Drug Discovery and

Enzyme Inhibition in Drug Discovery and Development || The Role of Drug Metabolism in Drug Discovery

✍ Lu, Chuang; Li, Albert P. 📂 Article 📅 2009 🏛 John Wiley & Sons, Inc. ⚖ 893 KB

The Evolving Role of Drug Metabolism in

The Evolving Role of Drug Metabolism in Drug Discovery and Development

✍ Lilian G. Yengi; Louis Leung; John Kao 📂 Article 📅 2007 🏛 Springer US 🌐 English ⚖ 407 KB