๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development

โœ Scribed by Jan van der Greef; Aram Adourian; Pieter Muntendam; Robert N. McBurney

Book ID
119226356
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
572 KB
Volume
3
Category
Article
ISSN
1740-6749

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Role of drug metabolism in drug discover
Role of drug metabolism in drug discovery and development
โœ Gondi N. Kumar; Sekhar Surapaneni ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 300 KB ๐Ÿ‘ 1 views

## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t