Importance of CD80/CD86–CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells
✍ Scribed by Zhe Shi; Muhaimin Rifa’i; Young Ho Lee; Hiroshi Shiku; Ken-ichi Isobe; Haruhiko Suzuki
- Book ID
- 108782235
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 444 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0019-2805
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Although CD28 triggering provides an important co-stimulatory signal to T cells, blocking the CD80/CD86 -CD28 interaction with CTLA-4lg fusion protein is not sufficient for tolerance induction in vivo or in vitro. According to more recent data, interruption of the CD40 -CD154 interaction might compl
In mouse liver transplantation, tolerance is readily inducible. Recent studies have revealed that CD25+ CD4+ regulatory T cells play an important role in regulating various immune responses, including transplant tolerance. However, the contribution of these cells to tolerance in mouse liver transpla