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Implications of P16/CDKN2A deletion in pleural mesotheliomas

✍ Scribed by Ladanyi, Marc


Book ID
119319195
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
70 KB
Volume
49
Category
Article
ISSN
0169-5002

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To elucidate the possibility of the existence of multiple tumor suppressor genes on chromosome arm 9p, we performed genetic and epigenetic analyses of the CDKN2A/p16/MTS1 and CDKN2B/p15/MTS2 genes as well as homozygous deletion mapping of 9p in human lung carcinoma. To avoid overlooking genetic alte