✦ LIBER ✦

Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas

✍ Scribed by Yasuhiro Ono; Keisuke Ueki; J. T. Joseph; D. N. Louis

Publisher: Springer-Verlag
Year: 1996
Tongue: English
Weight: 48 KB
Volume: 91
Category: Article
ISSN: 0001-6322
DOI: 10.1007/s004010050419

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Absence of p16 gene (CDKN2) deletions in

Absence of p16 gene (CDKN2) deletions in microdissected primary breast carcinoma specimens

✍ Jacqueline E. Calvano; Elisa B. Rush; Lee K. Tan; Paul Peter Rosen; Patrick I. B 📂 Article 📅 1997 🏛 Springer 🌐 English ⚖ 1021 KB

Association of CDKN2A (p16)/CDKN2B (p15)

Association of CDKN2A (p16)/CDKN2B (p15) alterations and homozygous chromosome arm 9p deletions in human lung carcinoma

✍ Kunihiro Hamada; Takashi Kohno; Masashi Kawanishi; Susumu Ohwada; Jun Yokota 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB 👁 1 views

To elucidate the possibility of the existence of multiple tumor suppressor genes on chromosome arm 9p, we performed genetic and epigenetic analyses of the CDKN2A/p16/MTS1 and CDKN2B/p15/MTS2 genes as well as homozygous deletion mapping of 9p in human lung carcinoma. To avoid overlooking genetic alte

The 9p21 region in bladder cancer cell l

The 9p21 region in bladder cancer cell lines: large homozygous deletions inactivate the CDKN2, CDKN2B and MTAP genes

✍ Stadler, W. M. ;Olopade, O. I. 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 890 KB

Homozygous and hemizygous deletions of 9p21 are the earliest and most common genetic alteration in bladder cancer. The identification of two cell cycle regulators, CDKN2 and CDKN2B, that map to the common region of deletion has prompted the hypothesis that they are critical tumor suppressor genes in

Low frequency of p16/CDKN2 gene mutation

Low frequency of p16/CDKN2 gene mutations in esophageal carcinomas

✍ Asunción Esteve; Ghyslaine Martel-Planche; Bakary S. Sylla; Monica Hollstein; Pi 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 515 KB

Mutational analysis of the pl6ICDKN2 gene was conducted by direct sequencing of the whole coding sequence (exom 1-3 and flanking splicing sites) in 21 esophageal squamous-cell carcinomas and 3 adenocarcinomas from a high-incidence area of Italy. Two inactivating mutations were found in exon I of the

Alterations of retinoblastoma, p53, p16(

Alterations of retinoblastoma, p53, p16(CDKN2), and p15 genes in human astrocytomas

✍ Toshihide Tsuzuki; Shigeru Tsunoda; Toshisuke Sakaki; Noboru Konishi; Yoshio Hia 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 637 KB

## BACKGROUND. Alterations of the suppressor genes, such as the retinoblastoma (RB), p53, pl6(CDKN2), and p15 genes, have been reported in human gliomas. These genes have been suggested as the cell cycle regulatory genes at the G,-S checkpoint.

Small deletions but not methylation unde

Small deletions but not methylation underlie CDKN2A/p16 loss of expression in conventional osteosarcoma

✍ Alexander B. Mohseny; Chris Tieken; Pieter A. van der Velden; Karoly Szuhai; Car 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 340 KB

## Abstract Conventional osteosarcoma is characterized by rapid growth, high local aggressiveness, and metastasizing potential. Patients developing lung metastases experience poor prognosis despite extensive chemotherapy regimens and surgical interventions. Previously we identified a subgroup of os